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Ανατροπή δεδομένων από άρθρο - μελέτη του Prof. Dr. Günter Kampf (University Medicine Greifswald, Institute for Hygiene and Environmental Medicine, Ferdinand-Sauerbruch-Strasse, 17475 Greifswald, Germany) που δημοσιεύεται στο ιατρικό περιοδικό The Lancet (
https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(21)00258-1/fulltext?s=08#%20):
High COVID-19 vaccination rates were expected to reduce transmission of
SARS-CoV-2 in populations by reducing the number of possible sources for
transmission and thereby to reduce the burden of COVID-19 disease.
Recent data, however, indicate that the epidemiological relevance of
COVID-19 vaccinated individuals is increasing. In the UK it was
described that secondary attack rates among household contacts exposed
to fully vaccinated index cases was similar to household contacts
exposed to unvaccinated index cases (25% for vaccinated vs 23% for
unvaccinated). 12 of 31 infections in fully vaccinated household
contacts (39%) arose from fully vaccinated epidemiologically linked
index cases. Peak viral load did not differ by vaccination status or
variant type [
].
In Germany, the rate of symptomatic COVID-19 cases among the fully
vaccinated (“breakthrough infections”) is reported weekly since 21. July
2021 and was 16.9% at that time among patients of 60 years and older [
]. This proportion is increasing week by week and was 58.9% on 27. October 2021 (
Figure 1)
providing clear evidence of the increasing relevance of the fully
vaccinated as a possible source of transmission. A similar situation was
described for the UK. Between week 39 and 42, a total of 100.160
COVID-19 cases were reported among citizens of 60 years or older. 89.821
occurred among the fully vaccinated (89.7%), 3.395 among the
unvaccinated (3.4%) [
].
One week before, the COVID-19 case rate per 100.000 was higher among
the subgroup of the vaccinated compared to the subgroup of the
unvaccinated in all age groups of 30 years or more. In Israel a
nosocomial outbreak was reported involving 16 healthcare workers, 23
exposed patients and two family members. The source was a fully
vaccinated COVID-19 patient. The vaccination rate was 96.2% among all
exposed individuals (151 healthcare workers and 97 patients). Fourteen
fully vaccinated patients became severely ill or died, the two
unvaccinated patients developed mild disease [
].
The US Centres for Disease Control and Prevention (CDC) identifies four
of the top five counties with the highest percentage of fully
vaccinated population (99.9–84.3%) as “high” transmission counties [
].
Many decisionmakers assume that the vaccinated can be excluded as a
source of transmission. It appears to be grossly negligent to ignore the
vaccinated population as a possible and relevant source of transmission
when deciding about public health control measures.
Figure 1Vaccination
rates and proportions of fully vaccinated people among symptomatic
COVID-19 cases (≥ 60 years) in Germany between 21. July and 27. October
2021 based on the weekly reports from the Robert Koch-Institute
Σε διαφορετική περίπτωση μπορείτε να ακούσετε και μια ηχητική παρουσίαση του άρθρου από το Γιώργο Σαχίνη, μετά το 8ο λεπτό
